Matrixyl Serums Are the Hero Beauty Essential That Could Delay Your Next Botox Appointment

Beauty

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matrixyl serums
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Best Overall

The Ordinary Matrixyl 10% + HA High-Strength Wrinkle Support Serum

Matrixyl 10% + HA High-Strength Wrinkle Support Serum

Pros
  • Affordable
Cons
  • Some find the texture a bit sticky

This serum blends matrixyl peptides and hyaluronic acid for a potent formula that boosts elasticity and hydrates skin. The formula includes 10 percent matrixyl, which helps to target fine lines and wrinkles and promote collagen production.

Key ingredients: Matrixyl peptides, hyaluronic acid

Size: 30 mL

Ulta rating: 4.5/5

Our expert says: “The Ordinary’s Matrixyl 10% + HA is popular for their effective blend of peptides and hydration at an affordable price.”—Gohara

Best to Use With Injectables

Peter Thomas Roth Peptide Skinjection Amplified Wrinkle-Fix Serum

Peptide Skinjection Amplified Wrinkle-Fix Serum

Pros
  • Aims to help extend your injectables
Cons
  • Some find the texture to be a bit gritty

Consider this serum a secret weapon for targeting fine lines and wrinkles. Made with a peptide complex that includes both matrixyl peptides and argireline, it’s meant to work as a supplement to your injectables—this serum claims to help extend your botox by up to six months.

Key ingredients: Matrixyl peptides, argireline

Size: 30 mL

Dermstore rating: 4/5

A Dermstore reviewer says: “I bought this product to use as a supplement with Botox. I found that it helped keep my forehead lines relaxed longer between appointments, although I didn’t see much difference around my crows feet . The consistency is creamy and feels moisturizing, and I liked the ingredient list. I’m back for a refill.”

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Best for Skin Repair

Arcona Advanced A Serum

Advanced A Serum

Pros
  • Retinal helps cellular turnover
Cons
  • Results take time

This overnight serum uses a blend of matrixyl and antioxidant-rich chrysin, a flavinoid found in honey to help boost elasticity and collagen. It also has retinal, which helps to speed up cellular turnover to smooth and brighten skin. The ingredient list also includes arctic cloudberry, which helps shield skin from environmental damage.

Key ingredients: Matrixyl peptides, chrysin, retinal, arctic cloudberry

Size: 1.17 oz.

Dermstore rating: 4.6/5

A Dermstore reviewer says: “I’ve been using this on and off for a year, and I notice a huge difference when I use it. It makes my wrinkles less noticeable and my skin tight the next morning!”

Best for Calming

Timeless Skin Care Matrixyl 3000 Serum

Matrixyl 3000 Serum

Pros
  • Aloe and hyaluronic acid help soothe and moisturize skin
Cons
  • Some reviewers didn’t notice a big difference after using

This serum is meant to fit seamlessly into any skin-care routine and can be used daily. It’s made with matrixyl peptides to boost collagen synthesis and hyaluronic acid and aloe to plump and soothe skin.

Key ingredients: Matrixyl peptides, hyaluronic acid, aloe

Size: 1 oz.

Amazon rating: 4.5/5

An Amazon reviewer says: “This bottle lasted me a year! I have been using this in the morning along with tretinoin every few days at night, and my skin looks so much better. I decided at 35 I needed to step up my skin care, and this product definitely helped! I like it in the morning because it absorbs so well. My fine lines are practically gone!”

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Best for Firming

Asterwood Matrixyl 3000 + Argireline Serum with Hyaluronic Acid

Matrixyl 3000 + Argireline Serum with Hyaluronic Acid

Pros
  • Matrixyl and argireline work together to firm
Cons
  • Some reviewers found it to be a bit drying

With almost 2,000 five-star ratings, this matrixyl serum is a best-seller on Amazon for a reason. In this serum, matrixyl and argireline work together to boost collagen and elastin, repair damage, and reduce the appearance of fine lines and wrinkles on skin.

Key ingredients: Matrixyl peptides, argireline

Size: 4 oz.

Amazon rating: 4.4/5

An Amazon reviewer says: “I love how firm and calm my skin looks and feels after using this! My skin is generally quite sensitive and it feels so nourished after I apply it. I’m so happy I discovered this serum to add to my beauty routine. It’s so effective I barely use my other skin-care products anymore.”

What are the benefits of using a matrixyl serum?

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If you want tighter, smoother skin, matrixyl serums might be the perfect addition to your skin-care routine. “Matrixyl serum helps improve skin elasticity, smoothness, and overall firmness, making skin look more youthful over time,” says Gohara. Many matrixyl serums are also formulated with hydrating ingredients, so they also help keep skin moisturized and nourished.

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What should someone look for when choosing a matrixyl serum?

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If you want to get the most out of a matrixyl serum, there are a few guidelines to follow. “Look for a high concentration of matrixyl peptides, ideally paired with hydrating ingredients like hyaluronic acid, to enhance its effectiveness,” says Gohara. A good rule of thumb is to look for about a 10 percent concentration of matrixyl peptides.

Are there any drawbacks to using a matrixyl serum?

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As with any new skin-care products, it’s a good idea to do a patch test before you use a matrixyl serum. “Some people may experience mild irritation or breakouts, so it’s important to test first, especially for sensitive skin,” says Gohara.

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Meet the expert

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Mona Gohara, MD, is the associate clinical professor of dermatology at Yale School of Medicine.

Why trust ELLE beauty?

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As a leading publisher of fashion, lifestyle, and beauty content, ELLE.com is committed to highlighting the best products in various categories by personally testing the latest and most innovative products, interviewing countless experts, and vetting customer-loved items. For this piece, ELLE beauty editor Katie Berohn interviewed a dermatologist and found the best matrixyl serums on the market.

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Shop More ELLE Beauty Essentials

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Headshot of Katie Berohn

Katie Berohn is ELLE’s beauty editor. Previously, she held the same title at Who What Wear, where she was promoted from associate beauty editor. She’s written for publications like The Cut, Cosmopolitan, Good Housekeeping, and Mashable. Her interests include fragrance, vintage shopping, hot yoga, food, travel, music, books, and attempting to make every NYT Cooking recipe. She’s on the endless hunt to find the perfect shade of red lipstick.

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